Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

Yolk sac (YS) hematopoiesis is critical for the survival of the embryo and a major source of tissue-resident macrophages that persist into adulthood. Yet, the transcriptional and epigenetic regulation of YS hematopoiesis remains poorly characterized. Here we report that the epigenetic regulator Ezh2...

Celý popis

Podrobná bibliografie
Hlavní autoři: Neo, WH, Meng, Y, Rodriguez-Meira, A, Fadlullah, MZH, Booth, CAG, Azzoni, E, Thongjuea, S, de Bruijn, MFTR, Jacobsen, SEW, Mead, AJ, Lacaud, G
Médium: Journal article
Jazyk:English
Vydáno: Springer Nature 2021