Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

Yolk sac (YS) hematopoiesis is critical for the survival of the embryo and a major source of tissue-resident macrophages that persist into adulthood. Yet, the transcriptional and epigenetic regulation of YS hematopoiesis remains poorly characterized. Here we report that the epigenetic regulator Ezh2...

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Main Authors: Neo, WH, Meng, Y, Rodriguez-Meira, A, Fadlullah, MZH, Booth, CAG, Azzoni, E, Thongjuea, S, de Bruijn, MFTR, Jacobsen, SEW, Mead, AJ, Lacaud, G
格式: Journal article
语言:English
出版: Springer Nature 2021