Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells

We have previously reported an antigen-specific protocol to induce transplant tolerance and linked suppression to human embryonic stem cell (hESC)-derived tissues in immunocompetent mice through coreceptor and costimulation blockade. However, the exact mechanisms of acquired immune tolerance in this...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Leung, C, Yang, K, Li, X, Chan, V, Ku, M, Waldmann, H, Hori, S, Tsang, J, Lo, Y, Lui, K
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: BioMed Central 2018