Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells

Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells

We have previously reported an antigen-specific protocol to induce transplant tolerance and linked suppression to human embryonic stem cell (hESC)-derived tissues in immunocompetent mice through coreceptor and costimulation blockade. However, the exact mechanisms of acquired immune tolerance in this...

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Bibliographic Details
Main Authors:	Leung, C, Yang, K, Li, X, Chan, V, Ku, M, Waldmann, H, Hori, S, Tsang, J, Lo, Y, Lui, K
Format:	Journal article
Language:	English
Published:	BioMed Central 2018

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