Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55).

The complement regulatory protein decay accelerating factor (DAF; CD55), inhibits the alternative complement pathway by accelerating decay of the convertase enzymes formed by C3b and factor B. We show, using surface plasmon resonance, that in the absence of Mg(2+), DAF binds C3b, factor B, and the B...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Harris, C, Abbott, R, Smith, R, Morgan, B, Lea, S
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2005