MR venography of the human brain using susceptibility weighted imaging at very high field strength.
OBJECTIVE: We investigate the implications of high magnetic field strength on MR venography based on susceptibility-weighted imaging (SWI) and estimate the optimum echo time to obtain maximum contrast between blood and brain tissue. MATERIALS AND METHODS: We measured tissue contrast and T2* relaxat...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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2008
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| _version_ | 1797073086582882304 |
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| author | Koopmans, P Manniesing, R Niessen, W Viergever, M Barth, M |
| author_facet | Koopmans, P Manniesing, R Niessen, W Viergever, M Barth, M |
| author_sort | Koopmans, P |
| collection | OXFORD |
| description | OBJECTIVE: We investigate the implications of high magnetic field strength on MR venography based on susceptibility-weighted imaging (SWI) and estimate the optimum echo time to obtain maximum contrast between blood and brain tissue. MATERIALS AND METHODS: We measured tissue contrast and T2* relaxation times at 7 T of gray matter, white matter, and venous blood in vivo. RESULTS: T2* relaxation times of gray matter, white matter, and venous blood in vivo yielded 32.9 +/- 2.3, 27.7 +/- 4.3, and 7.4 +/- 1.4 ms, respectively. Optimum TE was found to be 15 ms which is supported by theoretical considerations. Using this optimum TE, we acquired 3D high resolution datasets with a large volume coverage in a short measurement time that show very detailed microanatomical structures of the human brain such as intracortical veins and laminar cortical substructures. CONCLUSIONS: By applying optimised vessel filters (vesselness filter and vessel enhancing diffusion) whole brain MR venograms can be obtained at 7 T with a significantly reduced measurement time compared to 3 T. |
| first_indexed | 2024-03-06T23:16:57Z |
| format | Journal article |
| id | oxford-uuid:6775a19c-9e24-4fad-a4e3-f2a1b6187a22 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:16:57Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:6775a19c-9e24-4fad-a4e3-f2a1b6187a222022-03-26T18:38:23ZMR venography of the human brain using susceptibility weighted imaging at very high field strength.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6775a19c-9e24-4fad-a4e3-f2a1b6187a22EnglishSymplectic Elements at Oxford2008Koopmans, PManniesing, RNiessen, WViergever, MBarth, M OBJECTIVE: We investigate the implications of high magnetic field strength on MR venography based on susceptibility-weighted imaging (SWI) and estimate the optimum echo time to obtain maximum contrast between blood and brain tissue. MATERIALS AND METHODS: We measured tissue contrast and T2* relaxation times at 7 T of gray matter, white matter, and venous blood in vivo. RESULTS: T2* relaxation times of gray matter, white matter, and venous blood in vivo yielded 32.9 +/- 2.3, 27.7 +/- 4.3, and 7.4 +/- 1.4 ms, respectively. Optimum TE was found to be 15 ms which is supported by theoretical considerations. Using this optimum TE, we acquired 3D high resolution datasets with a large volume coverage in a short measurement time that show very detailed microanatomical structures of the human brain such as intracortical veins and laminar cortical substructures. CONCLUSIONS: By applying optimised vessel filters (vesselness filter and vessel enhancing diffusion) whole brain MR venograms can be obtained at 7 T with a significantly reduced measurement time compared to 3 T. |
| spellingShingle | Koopmans, P Manniesing, R Niessen, W Viergever, M Barth, M MR venography of the human brain using susceptibility weighted imaging at very high field strength. |
| title | MR venography of the human brain using susceptibility weighted imaging at very high field strength. |
| title_full | MR venography of the human brain using susceptibility weighted imaging at very high field strength. |
| title_fullStr | MR venography of the human brain using susceptibility weighted imaging at very high field strength. |
| title_full_unstemmed | MR venography of the human brain using susceptibility weighted imaging at very high field strength. |
| title_short | MR venography of the human brain using susceptibility weighted imaging at very high field strength. |
| title_sort | mr venography of the human brain using susceptibility weighted imaging at very high field strength |
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