The effects of mutational processes and selection on driver mutations across cancer types
Epidemiological evidence has long associated environmental mutagens with increased cancer risk. However, links between specific mutation-causing processes and the acquisition of individual driver mutations have remained obscure. Here we have used public cancer sequencing data from 11,336 cancers of...
Hlavní autoři: | Temko, D, Tomlinson, I, Severini, S, Schuster-Boeckler, P, Graham, T |
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Médium: | Journal article |
Vydáno: |
Springer Nature
2018
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