The effects of mutational processes and selection on driver mutations across cancer types

Epidemiological evidence has long associated environmental mutagens with increased cancer risk. However, links between specific mutation-causing processes and the acquisition of individual driver mutations have remained obscure. Here we have used public cancer sequencing data from 11,336 cancers of...

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Detalhes bibliográficos
Main Authors: Temko, D, Tomlinson, I, Severini, S, Schuster-Boeckler, P, Graham, T
Formato: Journal article
Publicado em: Springer Nature 2018