Synthesis of azabicyclic systems using nitrogen-directed radical rearrangements.

Synthesis of azabicyclic systems using nitrogen-directed radical rearrangements.

Radical rearrangements are important transformations in organic synthesis. The stabilisation of alpha-nitrogen radicals is shown to be a useful effect for the control of radical rearrangements and is applied to the synthesis of a variety of azabicyclic frameworks. The utility of this method is illus...

Bibliografske podrobnosti
Main Authors:	Hodgson, D, Winning, L
Format:	Journal article
Jezik:	English
Izdano:	2007

Podobne knjige/članki

Development of two processes for the synthesis of bridged azabicyclic systems: intermolecular radical addition-homoallylic rearrangements leading to 2-azanorborn-5-enes and neophyl-type radical rearrangements to 2-azabenzonorbornanes.
od: Hodgson, D, et al.
Izdano: (2003)

Photocatalytic methods for the construction of azabicycles
od: Lazar, N
Izdano: (2024)

Nitrogen-directed free radical rearrangements
od: Bebbington, M, et al.
Izdano: (2002)

Radical cascades using enantioenriched 7-azabenzonorbornenes and their applications in synthesis
od: Hodgson, D, et al.
Izdano: (2008)

Radical cascades using enantioenriched 7-azabenzonorbornenes and their applications in synthesis.
od: Hodgson, D, et al.
Izdano: (2008)

Cycloaddition of phenyl azide to unsymmetrical azabicyclic alkenes
od: John R. Malpass, et al.
Izdano: (2002-09-01)

2-azabenzonorbornanes from 7-azabenzonorbornanols by a nitrogen-directed neophyl-type radical rearrangement.
od: Hodgson, D, et al.
Izdano: (2002)

Palladium-catalyzed cascade cyclization of ynamides to azabicycles.
od: Greenaway, R, et al.
Izdano: (2011)

Tandem intermolecular radical addition-rearrangement for azacycle synthesis
od: Hodgson, D, et al.
Izdano: (2004)

Rh-Catalyzed Hydroformylation-Initiated Bicyclization: Construction of Azabicyclic Systems
od: Wen-Hua Chiou, et al.
Izdano: (2020-02-01)

Radical cascades using enantioenriched 7-azabenzonorbornenes and their applications in synthesis
od: David M. Hodgson, et al.
Izdano: (2008-10-01)

Highly enantioenriched 2-azabenzonorbornenes from 7-azabenzonorbornadienes by asymmetric hydroboration-oxidation and tandem deoxygenation-rearrangement-electrophile trapping
od: Hodgson, D, et al.
Izdano: (2006)

Enantioselective access to isoquinuclidines by tropenone desymmetrization and homoallylic radical rearrangement: synthesis of (+)-ibogamine.
od: Hodgson, D, et al.
Izdano: (2005)

An epoxide rearrangement-radical rearrangement approach to 6-substituted 2-azabicyclo[2.2.1]-5-heptenes: Synthesis of an epibatidine analogue
od: Hodgson, D, et al.
Izdano: (1998)

An epoxide rearrangement - Radical rearrangement approach to 6-substituted 2-azabicyclo[2.2.1]-5-heptenes: Synthesis of an epibatidine analogue.
od: Maxwell, C, et al.
Izdano: (1999)

Unexpected Resistance to Base-Catalyzed Hydrolysis of Nitrogen Pyramidal Amides Based on the 7-Azabicyclic[2.2.1]heptane Scaffold
od: Diego Antonio Ocampo Gutiérrez de Velasco, et al.
Izdano: (2018-09-01)

6-Substituted 2-azabicyclo[2.2.1]hept-5-enes by nitrogen-directed radical rearrangement: Synthesis of an epibatidine analogue with high binding affinity at the nicotinic acetylcholine receptor
od: Hodgson, D, et al.
Izdano: (2001)

Synthesis of alpha-kainic acid from a 7-azabicyclo[2.2.1]heptadiene by tandem radical addition-homoallylic radical rearrangement.
od: Hodgson, D, et al.
Izdano: (2005)

A) Nitrogen-directed homoallylic free-radical rearrangements for the construction of bridged azacycles B) Studies on a total synthesis of the microbial immunosuppressive agent FR901483 C) Phosphinoboranes as bifunctional organocatalysts and ambiphilic ligands
od: Bebbington, M, et al.
Izdano: (2006)

Pericyclic and related rearrangements for the synthesis of nitrogen heterocyclic ring systems
od: Zhurakovskyi, O
Izdano: (2013)

Stereocontrolled syntheses of kainoid amino acids from 7-azabicyclo[2.2.1]heptadienes using tandem radical addition-homoallylic radical rearrangement.
od: Hodgson, D, et al.
Izdano: (2005)

The 1H NMR Spectroscopic Effect of Steric Compression Is Found in [3.3.1]Oxa- and Azabicycles and Their Analogues
od: Ziyu Zeng, et al.
Izdano: (2021-05-01)

Catalytic asymmetric synthesis of (+)-anthecotulide using enyne and Meyer-Schuster rearrangements.
od: Hodgson, D, et al.
Izdano: (2011)

Synthesis of the anti-HIV agent (-)-hyperolactone C by using oxonium ylide formation-rearrangement.
od: Hodgson, D, et al.
Izdano: (2011)

Radical Smiles Rearrangement: An Update
od: Ingrid Allart-Simon, et al.
Izdano: (2016-07-01)

A new approach to enantiopure β-endo-substituted azabicyclic proline analogues by base induced epimerization of a formyl derivative
od: Ana M. Gil, et al.
Izdano: (2006-09-01)

An enantioselective epoxide rearrangement - Claisen rearrangement approach to prostaglandins and (+)-iridomyrmecin
od: Hodgson, D, et al.
Izdano: (1997)

On the mechanism of base-induced rearrangements of epoxides to ketones: a formal synthesis of (S)-physoperuvine
od: Hodgson, D, et al.
Izdano: (1999)

Synthesis and rearrangement of alicyclic systems
od: McHale, P
Izdano: (1973)

2-Azabicyclo[2.2.1]hept-5-enes from 7-azabicyclo[2.2.1]heptadienes by tandem intermolecular radical addition-homoallylic radical rearrangement
od: Hodgson, D, et al.
Izdano: (2001)

Synthesis of (-)-xialenon A by enantioselective alpha-deprotonation-rearrangement of a meso-epoxide
od: Hodgson, D, et al.
Izdano: (2003)

Asymmetric synthesis of heterocycles via cation-directed cyclizations and rearrangements
od: Lamb, A, et al.
Izdano: (2014)

Synthesis of the anti-trypanosomal agent (±)-hydroxyanthecotulide by Cr(ii)-catalysed allylation and Meyer-Schuster rearrangement.
od: Hodgson, D, et al.
Izdano: (2012)

2-azabicyclo[2.2.1]-5-heptenes from 7-azabicyclo[2.2.1]heptadienes by tandem intermolecular radical addition - Homoallylic rearrangement.
od: Hodgson, D, et al.
Izdano: (2001)

Unusual Rearrangements of Radical Cations: The Role of Vibronic Coupling
od: Thomas Bally
Izdano: (2016-03-01)

A cycloaddition-rearrangement approach to the squalestatins
od: Hodgson, D, et al.
Izdano: (1996)

Electrochemical generation of nitrogen-centered radicals for organic synthesis
od: Na Chen, et al.
Izdano: (2021-05-01)

Studies towards a stereocontrolled synthesis of the tricarboxylate core of the zaragozic acids-squalestatins by a cycloaddition-rearrangement strategy
od: Hodgson, D, et al.
Izdano: (2000)

A remarkable base-induced rearrangement of epoxydisilanes
od: Hodgson, D, et al.
Izdano: (1996)

Enantioselective rearrangement of exo-norbornene oxide to nortricyclanol
od: Hodgson, D, et al.
Izdano: (1996)