Coincidence of cholinergic pauses, dopaminergic activation and depolarisation of spiny projection neurons drives synaptic plasticity in the striatum

Dopamine-dependent long-term plasticity is believed to be a cellular mechanism underlying reinforcement learning. In response to reward and reward-predicting cues, phasic dopamine activity potentiates the efficacy of corticostriatal synapses on spiny projection neurons (SPNs). Since phasic dopamine...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Reynolds, JNJ, Avvisati, R, Dodson, PD, Fisher, SD, Oswald, MJ, Wickens, JR
التنسيق: Journal article
اللغة:English
منشور في: Springer Nature 2022