Investigation of expression quantitative trait loci and regulatory genetic variants in primary human immune cells

Investigation of expression quantitative trait loci and regulatory genetic variants in primary human immune cells

<p>The post human genome sequence era has begun to explore various aspects of the functional genome in relation to disease including gene expression, genetic variation and epigenetics. The genetic determinants of common and complex phenotypes are difficult to resolve even though their heritabi...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक:	Makino, S
अन्य लेखक:	Knight, J
स्वरूप:	थीसिस
भाषा:	English
प्रकाशित:	2013
विषय:	Immunology Genetics (medical sciences) Molecular genetics Medical Sciences

समान संसाधन

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The functional consequences of autoimmune variants in the tyrosine kinase 2 gene region
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Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative-trait loci that influence variation in the human personality trait neuroticism
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Functional characterisation of a multiple sclerosis-associated genetic variant
द्वारा: Gregory, A
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Genetic studies in ulcerative colitis
द्वारा: Bryant, RV
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The role of genetic variation in glucokinase and glucokinase regulatory protein in diabetes and related traits
द्वारा: Beer, N, और अन्य
प्रकाशित: (2011)

Genetic, functional, and phenotypic analysis of human variants in the glucokinase regulatory protein gene
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प्रकाशित: (2012)

Allele specific gene expression in the major histocompatibility complex
द्वारा: Plant, K
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Epigenetic approaches to the study of macrophages in atherosclerosis
द्वारा: Reschen, M
प्रकाशित: (2015)

Epigenetic regulation of the myeloid cell lineage
द्वारा: Pliuskys, L
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Forward genetic and cellular studies of immune regulation: the roles of Carma1, Interleukin-10 and Gimap5
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Influence of genetic and environmental factors on the immunogenicity of Hib vaccine in Gambian twins
द्वारा: Lee, Y, और अन्य
प्रकाशित: (2006)

Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis
द्वारा: McMahon, R, और अन्य
प्रकाशित: (2011)

Analysis of the CD200R family
द्वारा: Akkaya, M
प्रकाशित: (2011)

The identification and characterisation of germline genetic variants that affect human cancer
द्वारा: Zeron-Medina Cuairan, J
प्रकाशित: (2013)

Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension
द्वारा: Tzenova Bell, J, और अन्य
प्रकाशित: (2006)

Genetic susceptibility to endometrial cancer
द्वारा: Cheng, T
प्रकाशित: (2015)

Preimplantation genetic diagnosis - new methods for the detection of genetic abnormalities in human preimplantation embryos
द्वारा: Konstantinidis, M
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Use of genome wide expression profiles in analysis of T cell dysfunction in Hepatitis C virus infection
द्वारा: Gupta, P
प्रकाशित: (2014)

Genetics and pathophysiology of coronal craniosynostosis revealed by next-generation DNA sequencing
द्वारा: Sharma, V
प्रकाशित: (2015)

Bias of selection on human copy-number variants
द्वारा: Nguyen, D, और अन्य
प्रकाशित: (2006)

Forward genetic analysis of mammalian immunity
द्वारा: Siggs, O, और अन्य
प्रकाशित: (2012)

Functional analysis of polymorphisms associated with osteoarthritis susceptibility that affect cis-regulation
द्वारा: Wilkins, J
प्रकाशित: (2008)

Genetics of ankylosing spondylitis
द्वारा: Karaderi, T
प्रकाशित: (2012)

Strong heterogeneity in mutation rate causes misleading hallmarks of natural selection on indel mutations in the human genome
द्वारा: Kvikstad, E, और अन्य
प्रकाशित: (2013)

Genetics determinants of vaccine responses
द्वारा: O'Connor, D
प्रकाशित: (2014)

Molecular Genetics of Language Impairment
द्वारा: Nudel, R
प्रकाशित: (2015)

B cell response to pneumococcal vaccines
द्वारा: Trück, J
प्रकाशित: (2014)

A new era for Type 2 diabetes genetics
द्वारा: Zeggini, E
प्रकाशित: (2007)

The peoples of Britain: population genetics, archaeology and linguistics
द्वारा: Royrvik, E
प्रकाशित: (2012)

Genetic mapping of variation in spatial learning in the mouse
द्वारा: Steinberger, D, और अन्य
प्रकाशित: (2003)

Human population structure and demographic history using genetic markers
द्वारा: Wilson, J, और अन्य
प्रकाशित: (2002)

Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to Type 2 diabetes
द्वारा: Jafar-Mohammadi, B, और अन्य
प्रकाशित: (2009)

Investigation of dyslexia and SLI risk variants in reading- and language-impaired subjects
द्वारा: Newbury, D, और अन्य
प्रकाशित: (2011)

A high-resolution single nucleotide polymorphism genetic map of the mouse genome
द्वारा: Shifman, S, और अन्य
प्रकाशित: (2006)

Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences.
द्वारा: Czyz, W, और अन्य
प्रकाशित: (2012)

Functional conservation of HTLV-1 Rex balances the immune pressure for sequence variation in the Rex gene
द्वारा: Smith, R, और अन्य
प्रकाशित: (1997)

Functional genomics of variation in response to infection: insights into severe sepsis and common variable immune deficiency disorders
द्वारा: Davenport, E
प्रकाशित: (2014)

On genetic variants underlying common disease
द्वारा: Hechter, E
प्रकाशित: (2011)

Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response.
द्वारा: Matsumiya, M, और अन्य
प्रकाशित: (2014)