Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: application to glycoprotein crystallization.

Effects of N-butyldeoxynojirimycin and the Lec3.2.8.1 mutant phenotype on N-glycan processing in Chinese hamster ovary cells: application to glycoprotein crystallization.

Heterologous gene expression in either (1) the glycosylation-defective, mutant Chinese hamster ovary cell line, Lec3.2.8.1, or (2) the presence of the alpha-glucosidase inhibitor, N-butyldeoxynojirimycin facilitates the trimming of N-linked glycans of glycoproteins to single N-acetylglucosamine (Glc...

Full description

Bibliographic Details
Main Authors:	Butters, T, Sparks, L, Harlos, K, Ikemizu, S, Stuart, D, Jones, E, Davis, S
Format:	Journal article
Language:	English
Published:	1999

Similar Items

N-butyldeoxygalactonojirimycin: a more selective inhibitor of glycosphingolipid biosynthesis than N-butyldeoxynojirimycin, in vitro and in vivo.
by: Andersson, U, et al.
Published: (2000)

NSAIDs increase survival in the Sandhoff disease mouse: synergy with N-butyldeoxynojirimycin.
by: Jeyakumar, M, et al.
Published: (2004)

Long-term non-hormonal male contraception in mice using N-butyldeoxynojirimycin.
by: Walden, C, et al.
Published: (2006)

N-butyldeoxynojirimycin causes weight loss as a result of appetite suppression in lean and obese mice.
by: Priestman, D, et al.
Published: (2008)

The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding.
by: Fischer, P, et al.
Published: (1995)

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.
by: Cox, T, et al.
Published: (2000)

3281 Management of Acute Rejection in Penile Allotransplantation
by: Michael Jonczyk, et al.
Published: (2019-03-01)

Severe endothelial dysfunction in the aorta of a mouse model of Fabry disease; partial prevention by N-butyldeoxynojirimycin treatment.
by: Heare, T, et al.
Published: (2007)

Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease.
by: Elstein, D, et al.
Published: (2004)

N -butyldeoxynojirimycin reduces growth and ganglioside content of experimental mouse brain tumours.
by: Ranes, M, et al.
Published: (2001)

Glycoproteins: rapid sequencing technology for N-linked and GPI anchor glycans
by: Rudd, P, et al.
Published: (1999)

Control in the N-linked glycoprotein biosynthesis pathway.
by: Butters, T
Published: (2002)

Carbasugar-thioether pseudodisaccharides related to N-glycan biosynthesis.
by: Cumpstey, I, et al.
Published: (2009)

Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice.
by: Denny, C, et al.
Published: (2010)

N-glycans from serum IgG and total serum glycoproteins specific for endometriosis
by: Zsuzsanna Kovács, et al.
Published: (2023-06-01)

The tetrameric plant lectin BanLec neutralizes HIV through bidentate binding to specific viral glycans.
by: Hopper, J, et al.
Published: (2017)

High level expression in Chinese hamster ovary cells of soluble forms of CD4 T lymphocyte glycoprotein including glycosylation variants.
by: Davis, S, et al.
Published: (1990)

N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery.
by: Pollock, S, et al.
Published: (2008)

N-butyldeoxynojirimycin (miglustat) ameliorates pulmonary fibrosis through inhibition of nuclear translocation of Smad2/3
by: Hiroyuki Nakamura, et al.
Published: (2023-04-01)

Total synthesis of the Glc(3)Man N-glycan tetrasaccharide
by: Ennis, S, et al.
Published: (2002)

Glycoprotein In Vitro N-Glycan Processing Using Enzymes Expressed in <i>E. coli</i>
by: Libo Zhang, et al.
Published: (2023-03-01)

Structural features of N-glycans linked to glycoproteins from oil palm pollen, an allergenic pollen
by: Kimura, Yoshinobu, et al.
Published: (2003)

BanLec-eGFP Chimera as a Tool for Evaluation of Lectin Binding to High-Mannose Glycans on Microorganisms
by: Zorana Lopandić, et al.
Published: (2021-01-01)

Function and 3D Structure of the <em>N</em>-Glycans on Glycoproteins
by: Yoshiki Yamaguchi, et al.
Published: (2012-07-01)

Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans.
by: Andres Garcia-Campos, et al.
Published: (2016-05-01)

Quality control of glycoproteins bearing truncated glycans in an ALG9-defective (CDG-IL) patient.
by: Vleugels, W, et al.
Published: (2009)

Glycan shield of the ebolavirus envelope glycoprotein GP
by: Weiwei Peng, et al.
Published: (2022-08-01)

An endoglycosidase with alternative glycan specificity allows broadened glycoprotein remodelling.
by: Goodfellow, J, et al.
Published: (2012)

El art. 400 LEC
by: Joan Picó Junoy
Published: (2023-05-01)

Comentarios a la LEC
by: Ignacio Colomer Hernández
Published: (2008-02-01)

N-Linked Glycosylation in Chinese Hamster Ovary Cells Is Critical for Insulin-like Growth Factor 1 Signaling
by: Rupashree Salvi, et al.
Published: (2022-11-01)

Oligosaccharide analysis and molecular modeling of soluble forms of glycoproteins belonging to the Ly-6, scavenger receptor, and immunoglobulin superfamilies expressed in Chinese hamster ovary cells.
by: Rudd, P, et al.
Published: (1999)

Heteroglycoclusters With Dual Nanomolar Affinities for the Lectins LecA and LecB From Pseudomonas aeruginosa
by: David Goyard, et al.
Published: (2019-10-01)

Endoplasmic reticulum-quality control pathway and endoplasmic reticulum-associated degradation mechanism regulate the N-glycoproteins and N-glycan structures in the diatom Phaeodactylum tricornutum
by: Jichen Chen, et al.
Published: (2022-10-01)

Unexpected structure for the N-terminal domain of hepatitis C virus envelope glycoprotein E1
by: El Omari, K, et al.
Published: (2014)

Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase.
by: Thompson, A, et al.
Published: (2012)

Synthesis and α-Glucosidase II inhibitory activity of valienamine pseudodisaccharides relevant to N-glycan biosynthesis.
by: Cumpstey, I, et al.
Published: (2011)

Molecular identification of Pseudomonas aeruginosa lectins (LecA and LecB) by using polymerase chain reaction
by: Ahmed N. Hami, et al.
Published: (2017-12-01)

Comentarios prácticos a la LEC
by: Vicente C. Guzmán Fluja, et al.
Published: (2009-02-01)

N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis
by: Mihaela-Olivia Dobrica, et al.
Published: (2020-06-01)