Conquering the synthesis and functionalization of bicyclo[1.1.1]pentanes

Bicyclo[1.1.1]pentanes (BCPs) have become established as attractive bioisosteres for para-substituted benzene rings in drug design. Conferring various beneficial properties compared with their aromatic “parents,” BCPs featuring a wide array of bridgehead substituents can now be accessed by an equiva...

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Hlavní autoři: Shire, BR, Anderson, EA
Médium: Journal article
Jazyk:English
Vydáno: American Chemical Society 2023