Conquering the synthesis and functionalization of bicyclo[1.1.1]pentanes
Bicyclo[1.1.1]pentanes (BCPs) have become established as attractive bioisosteres for para-substituted benzene rings in drug design. Conferring various beneficial properties compared with their aromatic “parents,” BCPs featuring a wide array of bridgehead substituents can now be accessed by an equiva...
| Main Authors: | , |
|---|---|
| פורמט: | Journal article |
| שפה: | English |
| יצא לאור: |
American Chemical Society
2023
|