Mortality rate associated with diabetes: outcomes from a general practice level analysis in England using the Royal College of General Practitioners (RCGP) database indicate stability over a 15 year period

<p><strong>Introduction:</strong>&nbsp;Total population mortality rates have been falling and life expectancy increasing for more than 30&nbsp;years. Diabetes remains a significant risk factor for premature death. Here we used the Oxford Royal College of General Practitione...

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मुख्य लेखकों: Heald, A, Stedman, M, Robinson, A, Davies, M, Livingston, M, Alshames, R, Moreno, G, Gadsby, R, Rayman, G, Gibson, M, de Lusignan, S, Whyte, M
स्वरूप: Journal article
भाषा:English
प्रकाशित: Springer 2022
विवरण
सारांश:<p><strong>Introduction:</strong>&nbsp;Total population mortality rates have been falling and life expectancy increasing for more than 30&nbsp;years. Diabetes remains a significant risk factor for premature death. Here we used the Oxford Royal College of General Practitioners Research and Surveillance Centre (RCGP RSC) practices to determine diabetes-related vs non-diabetes-related mortality rates.</p> <p><strong>Methods:</strong>&nbsp;RCGP RSC data were provided on annual patient numbers and deaths, at practice level, for those with and without diabetes across four age groups (&lt;&thinsp;50, 50&ndash;64, 65&ndash;79,&thinsp;&ge;&thinsp;80&nbsp;years) over 15&nbsp;years. Investment in diabetes control, as measured by the cost of primary care medication, was also taken from GP prescribing data.</p> <p><strong>Results:</strong>&nbsp;We included 527 general practices. Over the period 2004&ndash;2019, there was no significant change in life years lost, which varied between 4.6 and 5.1&nbsp;years over this period. The proportion of all diabetes deaths by age band was significantly higher in the 65&ndash;79 years age group for men and women with diabetes than for their non-diabetic counterparts. For the year 2019, 26.6% of deaths were of people with diabetes. Of this 26.6%, 18.5% would be expected from age group and non-diabetes status, while the other 8.1% would not have been expected&mdash;pro rata to nation, this approximates to approximately 40,000 excess deaths in people with diabetes vs the general population.</p> <p><strong>Conclusion:</strong>&nbsp;There remains a wide variation in mortality rate of people with diabetes between general practices in UK. The mortality rate and life years lost for people with diabetes vs non-diabetes individuals have remained stable in recent years, while mortality rates for the general population have fallen. Investment in diabetes management at a local and national level is enabling us to hold the ground regarding the life-shortening consequences of having diabetes as increasing numbers of people develop T2DM at a younger age.</p>