The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework
<h4>Background</h4> <p>HIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of languag...
| Main Authors: | , , , |
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| Format: | Journal article |
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BioMed Central
2016
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| _version_ | 1797073210008666112 |
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| author | Alcock, K Abubakar, A Newton, C Holding, P |
| author_facet | Alcock, K Abubakar, A Newton, C Holding, P |
| author_sort | Alcock, K |
| collection | OXFORD |
| description | <h4>Background</h4> <p>HIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population.</p> <h4>Methods</h4> <p>We compared language development in children exposed to HIV in utero to community controls (N = 262, 8–30 months) in rural Kenya, using locally adapted and validated communicative development inventories.</p> <h4>Results</h4> <p>The mean score of the younger HIV-exposed uninfected infants (8–15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures.</p> <h4>Conclusions</h4> <p>Our preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status.</p> |
| first_indexed | 2024-03-06T23:18:49Z |
| format | Journal article |
| id | oxford-uuid:680bfd4c-f40e-453e-8763-802310f1383c |
| institution | University of Oxford |
| last_indexed | 2024-03-06T23:18:49Z |
| publishDate | 2016 |
| publisher | BioMed Central |
| record_format | dspace |
| spelling | oxford-uuid:680bfd4c-f40e-453e-8763-802310f1383c2022-03-26T18:42:20ZThe effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative frameworkJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:680bfd4c-f40e-453e-8763-802310f1383cSymplectic Elements at OxfordBioMed Central2016Alcock, KAbubakar, ANewton, CHolding, P <h4>Background</h4> <p>HIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population.</p> <h4>Methods</h4> <p>We compared language development in children exposed to HIV in utero to community controls (N = 262, 8–30 months) in rural Kenya, using locally adapted and validated communicative development inventories.</p> <h4>Results</h4> <p>The mean score of the younger HIV-exposed uninfected infants (8–15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures.</p> <h4>Conclusions</h4> <p>Our preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status.</p> |
| spellingShingle | Alcock, K Abubakar, A Newton, C Holding, P The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework |
| title | The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework |
| title_full | The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework |
| title_fullStr | The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework |
| title_full_unstemmed | The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework |
| title_short | The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework |
| title_sort | effects of prenatal hiv exposure on language functioning in kenyan children establishing an evaluative framework |
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