T-B cell interaction inhibits spontaneous apoptosis of mature lymphocytes in Bcl-2-deficient mice.

Bcl-2 expression is tightly regulated during lymphocyte development. Mature lymphocytes in Bcl-2-deficient mice show accelerated spontaneous apoptosis in vivo and in vitro. Stimulation of Bcl-2-deficient lymphocytes by anti-CD3 antibody inhibited the spontaneous apoptosis not only in T cells but als...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Nakayama, K, Dustin, L, Loh, D
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: 1995