Novel APC-like properties of human NK cells directly regulate T cell activation.
Initiation of the adaptive immune response is dependent on the priming of naive T cells by APCs. Proteomic analysis of unactivated and activated human NK cell membrane-enriched fractions demonstrated that activated NK cells can efficiently stimulate T cells, since they upregulate MHC class II molecu...
Main Authors: | Hanna, J, Gonen-Gross, T, Fitchett, J, Rowe, T, Daniels, M, Arnon, T, Gazit, R, Joseph, A, Schjetne, K, Steinle, A, Porgador, A, Mevorach, D, Goldman-Wohl, D, Yagel, S, LaBarre, M, Buckner, J, Mandelboim, O |
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Format: | Journal article |
Language: | English |
Published: |
2004
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