Novel APC-like properties of human NK cells directly regulate T cell activation.

Novel APC-like properties of human NK cells directly regulate T cell activation.

Initiation of the adaptive immune response is dependent on the priming of naive T cells by APCs. Proteomic analysis of unactivated and activated human NK cell membrane-enriched fractions demonstrated that activated NK cells can efficiently stimulate T cells, since they upregulate MHC class II molecu...

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Hlavní autoři: Hanna, J, Gonen-Gross, T, Fitchett, J, Rowe, T, Daniels, M, Arnon, T, Gazit, R, Joseph, A, Schjetne, K, Steinle, A, Porgador, A, Mevorach, D, Goldman-Wohl, D, Yagel, S, LaBarre, M, Buckner, J, Mandelboim, O
Médium: Journal article
Jazyk:English
Vydáno: 2004

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