Human autoreactive T cells recognize CD1b and phospholipids.

In contrast with the common detection of T cells that recognize MHC, CD1a, CD1c, or CD1d proteins, CD1b autoreactive T cells have been difficult to isolate in humans. Here we report the development of polyvalent complexes of CD1b proteins and carbohydrate backbones (dextramers) and their use in iden...

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Detalhes bibliográficos
Principais autores: Van Rhijn, I, van Berlo, T, Hilmenyuk, T, Cheng, T, Wolf, B, Tatituri, R, Uldrich, A, Napolitani, G, Cerundolo, V, Altman, J, Willemsen, P, Huang, S, Rossjohn, J, Besra, G, Brenner, M, Godfrey, D, Moody, D
Formato: Journal article
Idioma:English
Publicado em: National Academy of Sciences 2016