A very stable cyclic DNA miniduplex with just two base pairs.
(Chemical Equation Presented) What goes around... Cyclic mini-DNA duplexes, as shown in the scheme, have been synthesized in high yield on the multimicromole scale by using click chemistry. These B-like duplexes are very stable and bind to drugs, such as distamycin A and 7-aminoactinomycin D. Circul...
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Detalhes bibliográficos
Principais autores: |
El-Sagheer, A,
Kumar, R,
Findlow, S,
Werner, J,
Lane, A,
Brown, T |
Formato: | Journal article
|
Idioma: | English |
Publicado em: |
2008
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