A very stable cyclic DNA miniduplex with just two base pairs.

(Chemical Equation Presented) What goes around... Cyclic mini-DNA duplexes, as shown in the scheme, have been synthesized in high yield on the multimicromole scale by using click chemistry. These B-like duplexes are very stable and bind to drugs, such as distamycin A and 7-aminoactinomycin D. Circul...

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Détails bibliographiques
Auteurs principaux: El-Sagheer, A, Kumar, R, Findlow, S, Werner, J, Lane, A, Brown, T
Format: Journal article
Langue:English
Publié: 2008

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