A very stable cyclic DNA miniduplex with just two base pairs.
(Chemical Equation Presented) What goes around... Cyclic mini-DNA duplexes, as shown in the scheme, have been synthesized in high yield on the multimicromole scale by using click chemistry. These B-like duplexes are very stable and bind to drugs, such as distamycin A and 7-aminoactinomycin D. Circul...
Main Authors: | El-Sagheer, A, Kumar, R, Findlow, S, Werner, J, Lane, A, Brown, T |
---|---|
格式: | Journal article |
語言: | English |
出版: |
2008
|
相似書籍
-
Very stable mismatch duplexes: structural and thermodynamic studies on tandem G.A mismatches in DNA.
由: Ebel, S, et al.
出版: (1992) -
Stable end-sealed DNA as robust nano-rulers for in vivo single-molecule fluorescence
由: Plochowietz, A, et al.
出版: (2016) -
Tension induces a base-paired overstretched DNA conformation.
由: Bosaeus, N, et al.
出版: (2012) -
Synthesis, Serum Stability and Cell Uptake of Cyclic and Hairpin Decoy Oligonucleotides for TCF/LEF and GLI Transcription Factors
由: El-Sagheer, A, et al.
出版: (2008) -
Click chemistry with DNA.
由: El-Sagheer, A, et al.
出版: (2010)