Investigating the role of APOE-ε4, a risk gene for Alzheimer's disease, on functional brain networks using magnetoencephalography

Investigating the role of APOE-ε4, a risk gene for Alzheimer's disease, on functional brain networks using magnetoencephalography

<p>Alzheimer's disease (AD) is developing into the single greatest healthcare challenge in the coming decades. The development of early and effective treatments that can prevent the pathological damage responsible for AD-related dementia is of utmost priority for healthcare authorities. T...

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Bibliografiske detaljer
Hovedforfatter:	Luckhoo, HT
Andre forfattere:	Woolrich, M
Format:	Thesis
Sprog:	English
Udgivet:	2013
Fag:	Biomedical engineering

Lignende værker

Temporal dynamics of resting state brain connectivity as revealed by magnetoencephalography
af: Baker, A
Udgivet: (2014)

Rate of brain aging and APOE ε4 are synergistic risk factors for Alzheimer’s disease
af: Glorioso, Christin A, et al.
Udgivet: (2021)

Rate of brain aging and APOE ε4 are synergistic risk factors for Alzheimer’s disease
af: Glorioso, Christin A., et al.
Udgivet: (2022)

APOEε4 and risk of Alzheimer’s disease – time to move forward
af: Iliya Lefterov, et al.
Udgivet: (2023-05-01)

Evidence that an <it>APOE </it>ε4 'double whammy' increases risk for Alzheimer's disease
af: Caesar Ina, et al.
Udgivet: (2012-04-01)

Investigating the electrophysiological basis of resting state networks using magnetoencephalography.
af: Brookes, M, et al.
Udgivet: (2011)

Dissecting the gene dose-effects of the APOE ε4 and ε2 alleles on hippocampal volumes in aging and Alzheimer's disease.
af: Christopher A Hostage, et al.
Udgivet: (2013-01-01)

Association between an Alzheimer's Disease-Related Index and APOE ε4 Gene Dose.
af: Frank Schraml, et al.
Udgivet: (2013-01-01)

Alzheimer's disease genetic risk variants beyond APOE ε4 predict mortality
af: Jesse Mez, et al.
Udgivet: (2017-01-01)

Modeling APOE ε4 familial Alzheimer’s disease in directly converted 3D brain organoids
af: Yunkyung Kim, et al.
Udgivet: (2024-08-01)

The Role of Magnetoencephalography in the Early Stages of Alzheimer’s Disease
af: David López-Sanz, et al.
Udgivet: (2018-08-01)

Identification of an APOE ε4–specific blood‐based molecular pathway for Alzheimer's disease risk
af: Qiushan Tao, et al.
Udgivet: (2023-10-01)

Polygenic score modifies risk for Alzheimer's disease in APOE ε4 homozygotes at phenotypic extremes
af: Aamira J. Huq, et al.
Udgivet: (2021-01-01)

Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome
af: Matthias Arnold, et al.
Udgivet: (2020-03-01)

Impact of sex and APOE-ε4 genotype on patterns of regional brain atrophy in Alzheimer's disease and healthy aging
af: Benoît Sauty, et al.
Udgivet: (2023-06-01)

Differences in resting-state brain networks and gray matter between APOE ε2 and APOE ε4 carriers in non-dementia elderly
af: Zhiyuan Wang, et al.
Udgivet: (2023-08-01)

Alterations in dorsal and ventral posterior cingulate connectivity in APOE ε4 carriers at risk of Alzheimer's disease
af: Rebecca Kerestes, et al.
Udgivet: (2015-10-01)

Impact of APOE ε4 and ε2 on plasma neurofilament light chain and cognition in autosomal dominant Alzheimer’s disease
af: Stephanie Langella, et al.
Udgivet: (2024-10-01)

The Neural Dynamics of Fronto-Parietal Networks in Childhood Revealed using Magnetoencephalography.
af: Astle, D, et al.
Udgivet: (2014)

Corrigendum: Differences in resting-state brain networks and gray matter between APOE ϵ2 and APOE ϵ4 carriers in non-dementia elderly
af: Zhiyuan Wang, et al.
Udgivet: (2024-01-01)

Detrimental Effects of ApoE ε4 on Blood–Brain Barrier Integrity and Their Potential Implications on the Pathogenesis of Alzheimer’s Disease
af: Kevin Kirchner, et al.
Udgivet: (2023-10-01)

Expert consensus on the standardized application of ApoE ε4 measurement in Alzheimer's disease
af: Expert Consensus Writing Group on ApoE ε4 and Alzheimer's Disease, et al.
Udgivet: (2024-08-01)

Effect of APOE ε4 genotype on amyloid-β and tau accumulation in Alzheimer’s disease
af: Min Seok Baek, et al.
Udgivet: (2020-10-01)

Differences in plasma metabolites related to Alzheimer's disease, APOE ε4 status, and ethnicity
af: Badri Vardarajan, et al.
Udgivet: (2020-01-01)

APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease
af: Elles Konijnenberg, et al.
Udgivet: (2020-05-01)

APOE-ε4 Carrier Status and Gut Microbiota Dysbiosis in Patients With Alzheimer Disease
af: Min Hou, et al.
Udgivet: (2021-02-01)

APOE ε4, Alzheimer’s disease neuropathology and sleep disturbance, in individuals with and without dementia
af: Jonathan Blackman, et al.
Udgivet: (2022-03-01)

APOE-ε4 and BIN1 increase risk of Alzheimer’s disease pathology but not specifically of Lewy body pathology
af: Seth Talyansky, et al.
Udgivet: (2023-09-01)

Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
af: Farid Rajabli, et al.
Udgivet: (2018-12-01)

The MAPT H1 Haplotype Is a Risk Factor for Alzheimer’s Disease in APOE ε4 Non-carriers
af: Pascual Sánchez-Juan, et al.
Udgivet: (2019-12-01)

APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.
af: Lei Yu, et al.
Udgivet: (2017-01-01)

Novel Alzheimer’s disease risk variants identified based on whole-genome sequencing of APOE ε4 carriers
af: Jong-Ho Park, et al.
Udgivet: (2021-05-01)

Inferring task-related networks using independent component analysis in magnetoencephalography.
af: Luckhoo, H, et al.
Udgivet: (2012)

The APOEε3/ε4 Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice
af: Kate E. Foley, et al.
Udgivet: (2022-03-01)

APOE ε4/ε4 homozygotes with early Alzheimer's disease show accelerated hippocampal atrophy and cortical thinning that correlates with cognitive decline
af: Susan Abushakra, et al.
Udgivet: (2020-01-01)

APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease
af: Marta Moreno-Rodriguez, et al.
Udgivet: (2025-01-01)

Selective effects of the APOE ε4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease
af: Mitchell K.P. Lai, et al.
Udgivet: (2006-06-01)

Midlife Lifestyle Activities Moderate APOE ε4 Effect on in vivo Alzheimer’s Disease Pathologies
af: So Yeon Jeon, et al.
Udgivet: (2020-02-01)

Deep brain stimulation for chronic pain investigated with magnetoencephalography.
af: Kringelbach, M, et al.
Udgivet: (2007)

The effects of APOE-ε4 on the BOLD response
af: Trachtenberg, A, et al.
Udgivet: (2010)