The association of squamous cell carcinoma of the vulva and lichen sclerosus: implications for management and follow up.

All cases of biopsy proven squamous cell carcinoma (SCC) of the vulva and of lichen sclerosus (LS) presenting to a district general hospital between 1984 and 1993 were studied. Twenty-eight cases of squamous cell carcinoma of the vulva were identified from histological specimens. Histological eviden...

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Bibliographic Details
Main Authors: Walkden, V, Chia, Y, Wojnarowska, F
Format: Journal article
Language:English
Published: 1997
Description
Summary:All cases of biopsy proven squamous cell carcinoma (SCC) of the vulva and of lichen sclerosus (LS) presenting to a district general hospital between 1984 and 1993 were studied. Twenty-eight cases of squamous cell carcinoma of the vulva were identified from histological specimens. Histological evidence of LS was found in 28.5% and clinical LS in 57%. There was poor correlation between clinical and histological findings when SCC arose on a background of LS. A second study of all cases of histological LS over the same period showed the incidence of SCC in vulval LS to be 7%.