Multicopy plasmids potentiate the evolution of antibiotic resistance in bacteria
Plasmids are thought to play a key role in bacterial evolution by acting as vehicles for horizontal gene transfer, but the role of plasmids as catalysts of gene evolution remains unexplored. We challenged populations of E. coli carrying blaTEM-1 β- lactamase gene on either the chromosome or a multic...
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| Format: | Journal article |
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Springer Nature
2016
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