Glucose and insulin homeostasis during the Jarisch-Herxheimer reaction
Plasma concentrations of glucose and insulin were measured in ten patients during the Jarisch-Herxheimer reaction of tetracycline-treated louse-borne relapsing fever. Plasma glucose fell significantly in eight of the ten patients associated with the peak of the reaction, but plasma insulin remained...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1985
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| _version_ | 1826276916217249792 |
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| author | Teklu, B Habte-Mlchael, A White, N Warrell, D Wright, D Turner, R |
| author_facet | Teklu, B Habte-Mlchael, A White, N Warrell, D Wright, D Turner, R |
| author_sort | Teklu, B |
| collection | OXFORD |
| description | Plasma concentrations of glucose and insulin were measured in ten patients during the Jarisch-Herxheimer reaction of tetracycline-treated louse-borne relapsing fever. Plasma glucose fell significantly in eight of the ten patients associated with the peak of the reaction, but plasma insulin remained low. Glucoregulation by insulin was therefore normal. This evidence questions the role of macrophage mediator-induced pancreatic insulin release in causing hypoglycaemia in borreliosis or bacterial endotoxicosis. © 1985. |
| first_indexed | 2024-03-06T23:21:01Z |
| format | Journal article |
| id | oxford-uuid:68b9d0b5-919c-4bf7-9c06-84e74e7fdb36 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T23:21:01Z |
| publishDate | 1985 |
| record_format | dspace |
| spelling | oxford-uuid:68b9d0b5-919c-4bf7-9c06-84e74e7fdb362022-03-26T18:46:58ZGlucose and insulin homeostasis during the Jarisch-Herxheimer reactionJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:68b9d0b5-919c-4bf7-9c06-84e74e7fdb36EnglishSymplectic Elements at Oxford1985Teklu, BHabte-Mlchael, AWhite, NWarrell, DWright, DTurner, RPlasma concentrations of glucose and insulin were measured in ten patients during the Jarisch-Herxheimer reaction of tetracycline-treated louse-borne relapsing fever. Plasma glucose fell significantly in eight of the ten patients associated with the peak of the reaction, but plasma insulin remained low. Glucoregulation by insulin was therefore normal. This evidence questions the role of macrophage mediator-induced pancreatic insulin release in causing hypoglycaemia in borreliosis or bacterial endotoxicosis. © 1985. |
| spellingShingle | Teklu, B Habte-Mlchael, A White, N Warrell, D Wright, D Turner, R Glucose and insulin homeostasis during the Jarisch-Herxheimer reaction |
| title | Glucose and insulin homeostasis during the Jarisch-Herxheimer reaction |
| title_full | Glucose and insulin homeostasis during the Jarisch-Herxheimer reaction |
| title_fullStr | Glucose and insulin homeostasis during the Jarisch-Herxheimer reaction |
| title_full_unstemmed | Glucose and insulin homeostasis during the Jarisch-Herxheimer reaction |
| title_short | Glucose and insulin homeostasis during the Jarisch-Herxheimer reaction |
| title_sort | glucose and insulin homeostasis during the jarisch herxheimer reaction |
| work_keys_str_mv | AT teklub glucoseandinsulinhomeostasisduringthejarischherxheimerreaction AT habtemlchaela glucoseandinsulinhomeostasisduringthejarischherxheimerreaction AT whiten glucoseandinsulinhomeostasisduringthejarischherxheimerreaction AT warrelld glucoseandinsulinhomeostasisduringthejarischherxheimerreaction AT wrightd glucoseandinsulinhomeostasisduringthejarischherxheimerreaction AT turnerr glucoseandinsulinhomeostasisduringthejarischherxheimerreaction |