Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains

Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains

Non-degradative ubiquitin chains and phosphorylation events govern signaling responses by innate immune receptors. The deubiquitinase CYLD in complex with SPATA2 is recruited to receptor signaling complexes by the ubiquitin ligase LUBAC and regulates Met1- and Lys63-linked polyubiquitin and receptor...

Полное описание

Библиографические подробности
Главные авторы:	Elliott, PR, Leske, D, Wagstaff, J, Schlicher, L, Berridge, G, Maslen, S, Timmermann, F, Ma, B, Fischer, R, Freund, SMV, Komander, D, Gyrd-Hansen, M
Формат:	Journal article
Язык:	English
Опубликовано:	Cell Press 2021

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