A mathematical model of the effects of hypoxia on the cell-cycle of normal and cancer cells
The evolution of the cell-cycle is known to be influenced by environmental conditions, including lack of extracellular oxygen (hypoxia). Notably, hypoxia appears to have different effects on normal and cancer cells. Whereas both experience hypoxia-induced arrest of the G1 phase of the cell-cycle (i....
Main Authors: | Alarcon, T, Byrne, H, Maini, P |
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Format: | Journal article |
Published: |
2004
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