A key centriole assembly interaction interface between human Plk4 and STIL appears to not be conserved in flies
A small number of proteins form a conserved pathway of centriole duplication. In humans and flies, the binding of Plk4/Sak to STIL/Ana2 initiates daughter centriole assembly. In humans, this interaction is mediated by an interaction between the Polo-Box-3 (PB3) domain of Plk4 and the coiled-coil dom...
| Главные авторы: | , , , |
|---|---|
| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
Company of Biologists
2017
|