A key centriole assembly interaction interface between human Plk4 and STIL appears to not be conserved in flies
A small number of proteins form a conserved pathway of centriole duplication. In humans and flies, the binding of Plk4/Sak to STIL/Ana2 initiates daughter centriole assembly. In humans, this interaction is mediated by an interaction between the Polo-Box-3 (PB3) domain of Plk4 and the coiled-coil dom...
Үндсэн зохиолчид: | Cottee, M, Johnson, S, Raff, J, Lea, S |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Company of Biologists
2017
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