A key centriole assembly interaction interface between human Plk4 and STIL appears to not be conserved in flies

A small number of proteins form a conserved pathway of centriole duplication. In humans and flies, the binding of Plk4/Sak to STIL/Ana2 initiates daughter centriole assembly. In humans, this interaction is mediated by an interaction between the Polo-Box-3 (PB3) domain of Plk4 and the coiled-coil dom...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Cottee, M, Johnson, S, Raff, J, Lea, S
التنسيق: Journal article
اللغة:English
منشور في: Company of Biologists 2017