Direct determination by 2H-NMR of the ionization state of phospholipids and of a local anaesthetic at the membrane surface.
Protonation and deprotonation of the primary amino group of phosphatidylethanolamine, and of the lipid phosphate groups of phosphatidylethanolamine with phosphatidylcholine, have been observed directly and isothermally in equimolar mixed fluid bilayers of the two phospholipids. In addition, the acid...
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1986
|