Inclusion of a dual signal sequence enhances the immunogenicity of a novel viral vectored vaccine against the capsular group B meningococcus
<strong>Background</strong> Disease caused by the capsular group B meningococcus (MenB) is the leading cause of infectious death in UK infants. A novel adenovirus-based vaccine encoding the MenB factor H binding protein (fHbp) with an N-terminal dual signal sequence induces high titres o...
Main Authors: | Sheerin, D, Dold, C, Silva-Reyes, L, Linder, A, Pollard, AJ, Rollier, CS |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2022
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