Gene expression and risk of leukemic transformation in myelodysplasia

Gene expression and risk of leukemic transformation in myelodysplasia

Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic disorders with a highly variable prognosis. To identify a gene expression-based classification of myelodysplasia with biological and clinical relevance, we performed a comprehensive transcriptomic analysis of myeloid n...

Bibliografski detalji
Glavni autori:	Shiozawa, Y, Malcovati, L, Gallì, A, Pellagatti, A, Karimi, M, Sato-Otsubo, A, Sato, Y, Suzuki, H, Yoshizato, T, Yoshida, K, Shiraishi, Y, Chiba, K, Makishima, H, Boultwood, J, Hellström-Lindberg, E, Miyano, S, Cazzola, M, Ogawa, S
Format:	Journal article
Jezik:	English
Izdano:	American Society of Hematology 2017

Slični predmeti

High-resolution genomic profiling of myelodysplasia (MDS) by microarray comparative genomic hybridization (CGH).
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Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations
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Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia
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Somatic Mutation of SF3B1, a Gene Encoding a Core Component of RNA Splicing Machinery, in Myelodysplasia with Ring Sideroblasts
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Gene expression profiling of day 7 erythroblasts from refractory anemia with ringed sideroblasts (RARS) and microarray-based identification of erythroid granulocyte-CSF (G-CSF) targets
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Identification of Prognostic Markers by Gene Expression Profiling In Myelodysplastic Syndrome Hematopoietic Stem Cells
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Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes.
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Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome
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