The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies.

Sas-6 and Ana2/STIL proteins are required for centriole duplication and the homooligomerisation properties of Sas-6 help establish the ninefold symmetry of the central cartwheel that initiates centriole assembly. Ana2/STIL proteins are poorly conserved, but they all contain a predicted Central Coile...

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Detalles Bibliográficos
Autores principales: Cottee, M, Muschalik, N, Johnson, S, Leveson, J, Raff, J, Lea, S
Formato: Journal article
Lenguaje:English
Publicado: eLife Sciences Publications 2015

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