The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies.
Sas-6 and Ana2/STIL proteins are required for centriole duplication and the homooligomerisation properties of Sas-6 help establish the ninefold symmetry of the central cartwheel that initiates centriole assembly. Ana2/STIL proteins are poorly conserved, but they all contain a predicted Central Coile...
Main Authors: | Cottee, M, Muschalik, N, Johnson, S, Leveson, J, Raff, J, Lea, S |
---|---|
格式: | Journal article |
語言: | English |
出版: |
eLife Sciences Publications
2015
|
相似書籍
-
SAS-6 oligomerization: the key to the centriole?
由: Cottee, M, et al.
出版: (2011) -
Building the Drosophila centriole: a structural investigation of the centriolar Proteins SAS-6, SAS-4 and Ana2
由: Cottee, M
出版: (2014) -
Drosophila Sas-6, Ana2 and Sas-4 self-organise into macromolecular structures that can be used to probe centriole and centrosome assembly
由: Gartenmann, L, et al.
出版: (2020) -
A key centriole assembly interaction interface between human Plk4 and STIL appears to not be conserved in flies
由: Cottee, M, et al.
出版: (2017) -
Drosophila Ana1 is required for centrosome assembly and centriole elongation
由: Saurya, S, et al.
出版: (2016)