The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies.
Sas-6 and Ana2/STIL proteins are required for centriole duplication and the homooligomerisation properties of Sas-6 help establish the ninefold symmetry of the central cartwheel that initiates centriole assembly. Ana2/STIL proteins are poorly conserved, but they all contain a predicted Central Coile...
Autores principales: | Cottee, M, Muschalik, N, Johnson, S, Leveson, J, Raff, J, Lea, S |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications
2015
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