Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.
The CD40-CD154 pathway is important in the pathogenesis of inflammatory bowel disease. Here we show that injection of an agonistic CD40 mAb to T and B cell-deficient mice was sufficient to induce a pathogenic systemic and intestinal innate inflammatory response that was functionally dependent on tum...
| প্রধান লেখক: | , , , , , , , , , , |
|---|---|
| বিন্যাস: | Journal article |
| ভাষা: | English |
| প্রকাশিত: |
2006
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Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
প্রকাশিত 2007
Journal article