Insights into pancreatic β cell energy metabolism using rodent β cell models

Insights into pancreatic β cell energy metabolism using rodent β cell models

Background : Mitochondrial diabetes is primarily caused by β-cell failure, a cell type whose unique properties are important in pathogenesis. Methods : By reducing glucose, we induced energetic stress in two rodent β-cell models to assess effects on cellular function. Results : Culturing rat insulin...

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Bibliografiske detaljer
Main Authors: Morten, K, Potter, M, Badder, L, Sivathondan, P, Dragovic, R, Neumann, A, Gavin, J, Shrestha, R, Reilly, S, Phadwal, K, Lodge, T, Borzychowski, A, Cookson, S, Mitchell, C, Morovat, A, Simon, A, Uusimaa, J, Hynes, J, Poulton, J
Format: Journal article
Sprog:English
Udgivet: F1000Research 2017

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