Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

STAT3, an essential transcription factor with pleiotropic functions, plays critical roles in the pathogenesis of autoimmunity. Despite recent data linking STAT3 with inflammatory bowel disease, exactly how it contributes to chronic intestinal inflammation is not known. Using a T cell transfer model...

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Bibliographic Details
Main Authors: Durant, L, Watford, W, Ramos, H, Laurence, A, Vahedi, G, Wei, L, Takahashi, H, Sun, H, Kanno, Y, Powrie, F, O'Shea, J
Format: Journal article
Language:English
Published: 2010

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