Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing.

microRNAs (miRNAs) silence gene expression by suppressing protein production and/or by promoting mRNA decay. To elucidate how silencing is accomplished, we screened an RNA interference library for suppressors of miRNA-mediated regulation in Drosophila melanogaster cells. In addition to proteins know...

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Những tác giả chính: Eulalio, A, Rehwinkel, J, Stricker, M, Huntzinger, E, Yang, S, Doerks, T, Dorner, S, Bork, P, Boutros, M, Izaurralde, E
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2007