The spinal muscular atrophy protein SMN affects Drosophila germline nuclear organization through the U body-P body pathway.
Survival motor neuron protein (SMN) is the determining factor for the human neurodegenerative disease spinal muscular atrophy (SMA). SMN is critical for small nuclear ribonucleoprotein (snRNP) assembly. Using Drosophila oogenesis as a model system, we show that mutations in smn cause abnormal nuclea...
| Autors principals: | , , |
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| Format: | Journal article |
| Idioma: | English |
| Publicat: |
2009
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