Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility

Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility

Genome-wide association studies (GWASs) have identified hundreds of loci associated with Crohn’s disease (CD). However, as with all complex diseases, robust identification of the genes dysregulated by noncoding variants typically driving GWAS discoveries has been challenging. Here, to complement GWA...

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Détails bibliographiques
Auteurs principaux: Sazonovs, A, Stevens, CR, Venkataraman, GR, Yuan, K, Avila, B, Abreu, MT, Ahmad, T, Allez, M, Ananthakrishnan, AN, Atzmon, G, Baras, A, Barrett, JC, Barzilai, N, Beaugerie, L, Beecham, A, Bernstein, CN, Bitton, A, Bokemeyer, B, Chan, A, Chung, D, Cleynen, I, Cosnes, J, Cutler, DJ, Daly, A, Damas, OM, Datta, LW, Dawany, N, Devoto, M, Dodge, S, Ellinghaus, E, Fachal, L, Farkkila, M, Faubion, W, Ferreira, M, Franchimont, D, Gabriel, SB, Ge, T, Georges, M, Gettler, K, Giri, M, Glaser, B, Goerg, S, Goyette, P, Graham, D, Hämäläinen, E, Haritunians, T, Heap, GA, Hiltunen, M, Hoeppner, M, Horowitz, JE, Simmons, A, Uhlig, HH
Format: Journal article
Langue:English
Publié: Springer Nature 2022

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