The mitochondrial cytochrome c N-terminal region is critical for maturation by holocytochrome c synthase.
The covalent attachment of heme to mitochondrial cytochrome c is catalysed by holocytochrome c synthase (HCCS, also called heme lyase). How HCCS functions and recognises the substrate apocytochrome is unknown. Here we have examined HCCS recognition of a chimeric substrate comprising a short mitochon...
Main Authors: | Stevens, J, Zhang, Y, Muthuvel, G, Sam, K, Allen, J, Ferguson, S |
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Format: | Journal article |
Language: | English |
Published: |
2011
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