Ebola disease: bridging scientific discoveries and clinical application

The west Africa Ebola disease epidemic (2014–16) marked a historic change of course for patient care during emerging infectious disease outbreaks. The epidemic response was a failure in many ways—a slow, cumbersome, and disjointed effort by a global architecture that was not fit for purpose for a ra...

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Những tác giả chính: Rojek, A, Fieggen, J, Apiyo, P, Caluwaerts, S, Fowler, RA, Kaleebu, P, Kojan, R, Lado, M, Lambe, T, Dunning, J, Horby, P
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Elsevier 2024
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author Rojek, A
Fieggen, J
Apiyo, P
Caluwaerts, S
Fowler, RA
Kaleebu, P
Kojan, R
Lado, M
Lambe, T
Dunning, J
Horby, P
author_facet Rojek, A
Fieggen, J
Apiyo, P
Caluwaerts, S
Fowler, RA
Kaleebu, P
Kojan, R
Lado, M
Lambe, T
Dunning, J
Horby, P
author_sort Rojek, A
collection OXFORD
description The west Africa Ebola disease epidemic (2014–16) marked a historic change of course for patient care during emerging infectious disease outbreaks. The epidemic response was a failure in many ways—a slow, cumbersome, and disjointed effort by a global architecture that was not fit for purpose for a rapidly spreading outbreak. In the most affected countries, health-care workers and other responders felt helpless—dealing with an overwhelming number of patients but with few, if any, tools at their disposal to provide high-quality care. These inadequacies, however, led to attention and innovation. The decade since then has seen remarkable achievements in clinical care for Ebola disease, including the approval of the first vaccines and treatments. In this paper, the first in a two-part Series, we reflect on this progress and provide expert summary of the modern landscape of Ebola disease, highlighting the priorities and ongoing activities aimed at further improving patient survival and wellbeing in the years ahead.
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spelling oxford-uuid:6aae9731-b4ff-4ece-814c-c46cbc8c4ea02025-01-07T12:53:55ZEbola disease: bridging scientific discoveries and clinical applicationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6aae9731-b4ff-4ece-814c-c46cbc8c4ea0EnglishSymplectic ElementsElsevier2024Rojek, AFieggen, JApiyo, PCaluwaerts, SFowler, RAKaleebu, PKojan, RLado, MLambe, TDunning, JHorby, PThe west Africa Ebola disease epidemic (2014–16) marked a historic change of course for patient care during emerging infectious disease outbreaks. The epidemic response was a failure in many ways—a slow, cumbersome, and disjointed effort by a global architecture that was not fit for purpose for a rapidly spreading outbreak. In the most affected countries, health-care workers and other responders felt helpless—dealing with an overwhelming number of patients but with few, if any, tools at their disposal to provide high-quality care. These inadequacies, however, led to attention and innovation. The decade since then has seen remarkable achievements in clinical care for Ebola disease, including the approval of the first vaccines and treatments. In this paper, the first in a two-part Series, we reflect on this progress and provide expert summary of the modern landscape of Ebola disease, highlighting the priorities and ongoing activities aimed at further improving patient survival and wellbeing in the years ahead.
spellingShingle Rojek, A
Fieggen, J
Apiyo, P
Caluwaerts, S
Fowler, RA
Kaleebu, P
Kojan, R
Lado, M
Lambe, T
Dunning, J
Horby, P
Ebola disease: bridging scientific discoveries and clinical application
title Ebola disease: bridging scientific discoveries and clinical application
title_full Ebola disease: bridging scientific discoveries and clinical application
title_fullStr Ebola disease: bridging scientific discoveries and clinical application
title_full_unstemmed Ebola disease: bridging scientific discoveries and clinical application
title_short Ebola disease: bridging scientific discoveries and clinical application
title_sort ebola disease bridging scientific discoveries and clinical application
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