Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.

The qnrS1 gene induces reduced susceptibility to fluoroquinolones in enterobacteria. We investigated the structure, antimicrobial susceptibility phenotype, and antimicrobial resistance gene characteristics of qnrS1 plasmids from hospitalized patients and community controls in southern Vietnam. We fo...

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Main Authors: Vien, L, Abuoun, M, Morrison, V, Thomson, N, Campbell, J, Woodward, M, Van Vinh Chau, N, Farrar, J, Schultsz, C, Baker, S
Format: Journal article
Language:English
Published: 2011
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author Vien, L
Abuoun, M
Morrison, V
Thomson, N
Campbell, J
Woodward, M
Van Vinh Chau, N
Farrar, J
Schultsz, C
Baker, S
author_facet Vien, L
Abuoun, M
Morrison, V
Thomson, N
Campbell, J
Woodward, M
Van Vinh Chau, N
Farrar, J
Schultsz, C
Baker, S
author_sort Vien, L
collection OXFORD
description The qnrS1 gene induces reduced susceptibility to fluoroquinolones in enterobacteria. We investigated the structure, antimicrobial susceptibility phenotype, and antimicrobial resistance gene characteristics of qnrS1 plasmids from hospitalized patients and community controls in southern Vietnam. We found that the antimicrobial susceptibilities, resistance gene characteristics, and plasmid structures of qnrS1 plasmids from the hospital differed from those from the community. Our data imply that the characteristics of the two plasmid groups are indicative of distinct selective pressures in the differing environments.
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spelling oxford-uuid:6ab6fee2-6cdb-4b4b-af8a-64d5af444c232022-03-26T18:59:18ZDifferential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:6ab6fee2-6cdb-4b4b-af8a-64d5af444c23EnglishSymplectic Elements at Oxford2011Vien, LAbuoun, MMorrison, VThomson, NCampbell, JWoodward, MVan Vinh Chau, NFarrar, JSchultsz, CBaker, SThe qnrS1 gene induces reduced susceptibility to fluoroquinolones in enterobacteria. We investigated the structure, antimicrobial susceptibility phenotype, and antimicrobial resistance gene characteristics of qnrS1 plasmids from hospitalized patients and community controls in southern Vietnam. We found that the antimicrobial susceptibilities, resistance gene characteristics, and plasmid structures of qnrS1 plasmids from the hospital differed from those from the community. Our data imply that the characteristics of the two plasmid groups are indicative of distinct selective pressures in the differing environments.
spellingShingle Vien, L
Abuoun, M
Morrison, V
Thomson, N
Campbell, J
Woodward, M
Van Vinh Chau, N
Farrar, J
Schultsz, C
Baker, S
Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.
title Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.
title_full Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.
title_fullStr Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.
title_full_unstemmed Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.
title_short Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.
title_sort differential phenotypic and genotypic characteristics of qnrs1 harboring plasmids carried by hospital and community commensal enterobacteria
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