Molecular detection of localized prostate cancer using quantitative methylation-specific PCR on urinary cells obtained following prostate massage.

PURPOSE: The diagnosis of localized prostate cancer is difficult due to a lack of cancer-specific biomarkers. Many patients require repeat prostate biopsies to diagnose the disease. We investigated whether aberrant promoter hypermethylation in prostatic fluid could reliably detect prostate cancer....

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Detalles Bibliográficos
Autores principales: Rouprêt, M, Hupertan, V, Yates, DR, Catto, J, Rehman, I, Meuth, M, Ricci, S, Lacave, R, Cancel-Tassin, G, de la Taille, A, Rozet, F, Cathelineau, X, Vallancien, G, Hamdy, F, Cussenot, O
Formato: Journal article
Lenguaje:English
Publicado: 2007