Asymmetric synthesis of (-)-(1R,7aS)-absouline

The most efficient and concise asymmetric synthesis of (-)-(1R,7aS)- absouline to date, which was accomplished in eight steps and 20% overall yield from commercially available starting materials, is described. The doubly diastereoselective conjugate addition of lithium (S)-N-benzyl-N-(α- methylbenzy...

Full description

Bibliographic Details
Main Authors: Davies, S, Fletcher, A, Lebée, C, Roberts, P, Thomson, J, Yin, J
Format: Journal article
Published: 2013