Lateral membrane waves constitute a universal dynamic pattern of motile cells.

Lateral membrane waves constitute a universal dynamic pattern of motile cells.

We have monitored active movements of the cell circumference on specifically coated substrates for a variety of cells including mouse embryonic fibroblasts and T cells, as well as wing disk cells from fruit flies. Despite having different functions and being from multiple phyla, these cell types sha...

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Bibliographic Details
Main Authors: Döbereiner, H, Dubin-Thaler, B, Hofman, J, Xenias, H, Sims, T, Giannone, G, Dustin, M, Wiggins, C, Sheetz, M
Format: Journal article
Language:English
Published: 2006
Description
Summary:We have monitored active movements of the cell circumference on specifically coated substrates for a variety of cells including mouse embryonic fibroblasts and T cells, as well as wing disk cells from fruit flies. Despite having different functions and being from multiple phyla, these cell types share a common spatiotemporal pattern in their normal membrane velocity; we show that protrusion and retraction events are organized in lateral waves along the cell membrane. These wave patterns indicate both spatial and temporal long-range periodic correlations of the actomyosin gel.

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