(ADP-ribosyl)hydrolases: Structural basis for differential substrate recognition and inhibition

Protein ADP-ribosylation is a highly dynamic post-translational modification. The rapid turnover is achieved, among others, by ADP-(ribosyl)hydrolases (ARHs), an ancient family of enzymes that reverses this modification. Recently ARHs came into focus due to their role as regulators of cellular stres...

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Podrobná bibliografie
Hlavní autoři: Rack, J, Ariza, A, Drown, B, Henfrey, C, Bartlett, E, Shirai, T, Hergenrother, P, Ahel, I
Médium: Journal article
Jazyk:English
Vydáno: Elsevier 2018