TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning.

TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning.

The rearrangement of nucleosomes along the DNA fiber profoundly affects gene expression, but little is known about how signalling reshapes the chromatin landscape, in three-dimensional space and over time, to allow establishment of new transcriptional programs.Using micrococcal nuclease treatment an...

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Hlavní autoři: Diermeier, S, Kolovos, P, Heizinger, L, Schwartz, U, Georgomanolis, T, Zirkel, A, Wedemann, G, Grosveld, F, Knoch, T, Merkl, R, Cook, P, Längst, G, Papantonis, A
Médium: Journal article
Jazyk:English
Vydáno: 2014

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